Suggested Use In Germany, physicians prescribe high dose proteolytic enzyme therapy during acute inflammations. Adults Acute Conditions: 5 tablets, every one to two hours until improvement is realized (up to three days), then reduce frequency and dose. Chronic Conditions: 3 to 5 tablets two to three times daily, one hours before or between meals. This dose is based on a 160-pound person. Children 1/2 or less of the adult dosage.